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Tuesday, 26th February 2008

Fixing the Prozac Nation

Peter Hoskin 8:51am

“Anti-depressants don't work” is the message splashed across the front pages this morning, after a research team from the University of Hull discovered that:

“The difference in improvement between patients taking placebos and people taking anti-depressants is not very great ....   There seems little reason to prescribe antidepressant medication to any but the most severely depressed patients.”

The finding isn't too surprising.  In 2004, the National Institute for Clinical Excellence (NICE) said that antidepressants shouldn't be prescribed in the case of mild depression, as the “risk-benefit ratio is poor”.  So why has the prescription of antidepressants soared, until significant numbers of children and even pets are using the drugs?

On Dr Martin Ingram's account, there are two reasons for the sorry situation – the day-to-day difficulties faced by GPs, and the war for hearts-and-minds waged by drugs companies:

“GPs are overstretched, under-resourced and have a limited amount of time to spend on each patient. Waiting lists for one of the most effective treatments for depression, cognitive behaviour therapy, are often as long as six months and counselling resources are often the first victims of cutbacks. It's frustrating.

It's no wonder it's so difficult to resist the pressure to prescribe, to deny patients what they can tend to see as their due. In Britain, too, pharmaceutical companies are eager to promote their wares to interested consumers.

Drug companies will keenly promote the effectiveness of their particular medication, but given the nebulous nature of depression, it's all too difficult to measure efficacy - something the Hull University report usefully establishes.”

The Government was forewarned about all this.  Back in 2006, Lord Layard told them that depression is Britain's "biggest social problem" - costing some £17 billion a year as well as blighting numerous individual lives - and that sufferers were all too often handed pills.  Nothing's changed since then.  Will this new revelation spur Brown into action?

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Corsair

February 26th, 2008 9:58am Report this comment

Citalopram works. I take it every day.

THX1138

February 26th, 2008 2:33pm Report this comment

I just rant at you Tories on this blog works a treat

RW

February 26th, 2008 3:04pm Report this comment

Aa any GP will confirm the healthiest, most effective and cheapest counter to depression is physical exercise - releases serotonin in the brain and endorphins which give you a natural feelgood factor. On another tack IMHO the best tonic for the nation as a whole would be to get shot of awful Brown and his appalling cronies at an early election. Most people would be turning cartwheels in the street for sheer joy. Better than a truckload of antidepressants!

David Lindsay

February 26th, 2008 5:10pm Report this comment

The best news in ages and ages. Prozac, Seroxet and the rest are, if anything, less effective than a nice cup of tea. Next on the hit list should be Ritalin. At least depression really exists. ADHD does not. It has been invented for commercial purposes, and its cult is based on the assumption that maleness is a medicable condition. The same has long been held to be the case about femaleness, where the "medication" in question in contraception, above all the Pill.

Daniel Livingstone

August 18th, 2009 6:10pm Report this comment

Anti depressants do work for many people. I suspect (Fundamentalist) Tories dont like them because the taking of a pill to make you feel better, which is what they are, would break the link between effort and reward (ie no need to "pull your socks up and knuckle down, its all in the mind you know). To these people this is an ethcial absolute (unless it applies to their own expenses that is.)

This offends their mean spirited view of the world and iits no surprise that Leon Kass and Willaim Safire, denizens of the more pernicious brand of American religious conservatism, have suggested that researhc into these interventions should be regulated (by which they means stopped.

Fortunately histroy books of the future will see these people in the same context as those who in the nineteenth century were against the use of anaesthetics to relieve the pain of child-birth.

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