‘I like to have a martini,/ Two at the very most./ After three I’m under the table,/ After four I’m under my host.’ I never fully appreciated the brilliance of that spurious quote of Dorothy Parker until I visited Dukes Bar in Mayfair. It used to be the case – it probably still is – that you may order no more than two martinis there owing to their potency. Had she not preferred whisky to gin, Parker might well have banged her fists on that table for a third. After one-and-a-half before dinner, however, this critic would be more inclined to dance on it.
Humans may respond to drink in different ways, but we are, in fact, better at processing it than most other primates. In ‘Why do we use intoxicants?’, a fun little documentary airing as part of the series Deeply Human on the World Service this Sunday, American musician Dessa talks to a researcher about the origins of our obsession. It is thought we first acquired a taste for alcohol when we experienced the ‘odour plume’ of dropped fruit that had gone bad and created ethanol. A genetic mutation, which occurred perhaps ten million years ago, made us 40 per cent more efficient than other animals at metabolising the alcohol. Not that you’d know it on a Saturday night.
It is easier to order ‘a little bag of meth’ in prohibitionist Tehran than a pizza
Drink may be ruinous to the body – ‘like playing the piano with boxing gloves on’, as another of the scientists says – but to the brain it can seem like a necessary ingredient for wit. Dessa quotes not only pseudo-Dorothy Parker, but F. Scott Fitzgerald (‘First you take a drink, then the drink takes a drink, then the drink takes you’) and, on another intoxicant, the late Robin Williams (‘Cocaine is God’s way of saying you’re making too much money’) to illustrate this point.

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