The Conservative majority of 23,000 was wiped out overnight in North Shropshire, with Liberal Democrat Helen Morgan winning the by-election by nearly 6,000 votes. Tory MPs are already making their frustrations known, with Roger Gale saying Boris Johnson has 'one more strike and he's out', and John Redwood saying it's 'Time to listen to Conservatives.' Is Boris Johnson's leadership in danger? Isabel Hardman speaks to Fraser Nelson and Katy Balls.
On the podcast, Isabel asks: 'You can change your staff, you can change your policies, but if the common denominator in all of these crises is Boris Johnson, what are you going to do?'