Even psychiatrists don’t know how the drugs they prescribe work

What is it like to go mad? Not so much developing depression or having a panic attack — which is wearyingly familiar to many of us — but to go properly mad, the sort of madness that involves delusions and police officers and locked psychiatric wards? Horatio Clare didn’t have to imagine what that was like for his book Heavy Light. It’s a memoir, subtitled ‘A Journey Through Madness, Mania and Healing’, and is an unsparing tale not just of what it was like for him to succumb to a psychotic episode but also of what it did to his family. The book starts with a skiing holiday in Italy