Inoculation

The concept of vaccination evolved from 18th-century inoculation practices and many people contributed to the accretion of knowledge. This book focuses on two individuals: the Quaker doctor Thomas Dimsdale, who, from his small Hertfordshire surgery, pioneered a simple smallpox immunisation; and Catherine the Great, who summoned him all the way to St Petersburg to inoculate her and the teenage Grand Duke Paul. Despite success all round, though, it turns out that anti-vaxxers are nothing new. After revealing the destructive force of smallpox – in one period of the 18th century, 400,000 perished annually in Europe – Lucy Ward, a journalist and former lobby correspondent, recapitulates the history of inoculation against

This timely book celebrates one of the most remarkable women of the 18th century. Lady Mary Wortley Montagu was so impressed by the Turkish technique of ‘engraftment’ to prevent smallpox that in 1721, exactly 300 years ago, she arranged for the first such inoculation in England — and, even more controversially, had it carried out on her own three-year-old daughter. Smallpox pus from a sufferer was carried in a walnut shell and applied to a cut made in her daughter’s arm. She discovered the technique too late to use it on herself. As a young woman and court beauty, she had contracted smallpox during one of the frequent epidemics that