Bioreactors and the art of manufacturing a Covid vaccine

When Covid struck and the quest for a vaccine began, the team at Oxford had a head start in that we were already working with the harmless common cold virus on which the AstraZeneca vaccine is based. ChAdOx — a contraction of ‘chimpanzee’, from which the virus was isolated, ‘adenovirus’ and ‘Oxford’ — is also being used to target diseases such as malaria, rabies, zika and Mers.